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Anti-TXNDC5 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TXNDC5 rabbit polyclonal |
Gene Name: | Thioredoxin domain-containing protein 5 |
Synonyms: | EndoPDI, ER protein 46, ERP46, Hcc 2, PDIA15, Thioredoxin like protein p46, TLP46, TXNDC5, UNQ364 |
Immunogen: | Recombinant protein corresponding to Mouse TXNDC5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | stomach, lymph node |
IHC | Human, Mouse, Rat | 1: 2000-1: 4000 | liver cancer, stomach cancer, placenta, tonsil, rectum, brain, spleen, lymph gland |
Background
TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.
Images
 | Western blot analysis of TXNDC5 (GB113311) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human stomach cancer using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human placenta using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human rectum using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human tonsil using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse lymph gland using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat lymph gland using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using TXNDC5 (GB113311) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat spleen using TXNDC5 (GB113311) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
