Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Translin/TSN rabbit polyclonal antibody |
Gene Name: | Translin |
Synonyms: | Component 3 of promoter of RISC, C3PO, Testis/brain RNA-binding protein, TB-RBP, REHF1, TRSLN, TSN |
Immunogen: | Recombinant protein corresponding to Mouse TSN |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q62348 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 1200 | lung |
Background
TSN, also named as Translin or Component 3 of promoter of RISC, is a 228 amino acid protein, which belongs to the translin family. TSN as a DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translations, mostly is involved in immunoglobulin T-cell receptor gene segments. TSN May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
Images
Immunohistochemistry of paraffin embedded mouse lung using Translin (GB111955) at dilution of 1:600 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using Translin (GB111955) at dilution of 1:600 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |