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Anti-uPA Receptor/U-PAR Rabbit pAb (100 μl)
| Reactivity: | H,M,R & R |
| Applications: | WB & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | uPA Receptor/U-PAR rabbit polyclonal antibody |
Gene Name: | Urokinase plasminogen activator surface receptor |
Synonyms: | U-PAR, CD87, Plaur, MO3, URKR, UPA receptor, Plasminogen activator urokinase receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse U-PAR |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Predicted MW. | 35 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | Q03405, P35456, P49616 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, kidney, brain |
IHC/IF | Rat | 1: 200-1: 400 | small intestine, thymus |
Background
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin.
Images
| Western blot analysis of PLAUR (GB112135) at dilution of 1: 500 |
| Immunofluorescence of paraffin embedded rat small intestine using PLAUR (GB112135) at dilution of 1: 200 (420x lens) |
| Immunofluorescence of paraffin embedded rat thymus using PLAUR (GB112135) at dilution of 1: 200 (550x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
