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Anti-UBE2E3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UBE2E3 rabbit polyclonal antibody |
Gene Name: | Ubiquitin-conjugating enzyme E2 E3 |
Synonyms: | E2 ubiquitin-conjugating enzyme E3, UbcM2, Ubiquitin carrier protein E3, Ubce4, Ubiquitin-conjugating enzyme E2-23 kDa, Ubiquitin-protein ligase E3, Ube2e3, UBCH9 |
Immunogen: | Recombinant protein corresponding to Mouse UBE2E3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 23 kDa |
Observed MW. | 23 kDa |
Uniprot ID: | Q969T4, P52483 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | testis, brain, kidney |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases or E3s. UBE2E3 is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48', as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Images
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Western blot analysis of Ube2e3 (GB111203) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
