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Anti-UBE2J1/UBC6e Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UBE2J1/UBC6e rabbit polyclonal antibody |
Gene Name: | Ubiquitin-conjugating enzyme E2 J1 |
Synonyms: | 2 ubiquitin-conjugating enzyme J1, Non-canonical ubiquitin-conjugating enzyme 1, NCUBE-1, Ube2j1, Ncube1 |
Immunogen: | Recombinant protein corresponding to Mouse UBE2J1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum |
Uniprot ID: | Q9Y385, Q9JJZ4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 1200 | colon, spleen |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.
Images
| Immunohistochemistry of paraffin embedded rat spleen using UBE2J1 (GB111868) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded mouse colon using UBE2J1 (GB111868) at dilution of 1:600 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
