Reactivity: | H,M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | UBE2S rabbit polyclonal |
Gene Name: | Ubiquitin-conjugating enzyme E2 S |
Synonyms: | E2-EPF, E2EPF, EPF5, UBE2S, Ubiquitin carrier protein S, Ubiquitin protein ligase S, E2 ubiquitin-conjugating enzyme S |
Immunogen: | Recombinant protein corresponding to Mouse UBE2S |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 1000 | MCF-7, U-2 OS, U-251MG, Jurkat, PC-3 |
Background
UBE2S(Ubiquitin-conjugating enzyme E2 S) is also named as E2EPF and belongs to the ubiquitin-conjugating enzyme family. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C) and a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Overexpression of UBE2S can increase tumor cell proliferation, invasion, and metastasis through the VHL-HIF pathway.
Images
Western blot analysis of UBE2S (GB113460) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |