Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | UCP2 rabbit polyclonal antibody |
Gene Name: | Mitochondrial uncoupling protein 2 |
Synonyms: | Solute carrier family 25 member 8, UCPH, Ucp2, Slc25a8, BMIQ4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse UCP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 33 kDa |
Uniprot ID: | P55851, P70406, P56500 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 250-1: 500 | heart, skeletal muscle |
Background
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
Images
Western blot analysis of UCP2 (GB112326) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |