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Anti-UEVLD Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UEVLD rabbit polyclonal antibody |
Gene Name: | Ubiquitin-conjugating enzyme E2 variant 3 |
Synonyms: | UEV-3, EV and lactate/malate dehydrogenase domain-containing protein, Uevld, Attp, Uev3 |
Immunogen: | Recombinant protein corresponding to Mouse UEVLD |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q3U1V6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 1300 | breast cancer, cervical cancer, colon, endometrial cancer, gastric cancer |
Background
UEV3, also known as EV and lactate/malate dehydrogenase domain-containing protein, is a 471 amino acid protein that contains one UEV (ubiquitin E2 variant) domain, which typically interacts with ubiquitin. UEV3 is thought to be a paralogue of tsg 101, a protein that exerts regulatory effects on E2 activity in cellular ubiquitination processes. With amino-terminal homology to the catalytic domain of ubiquitin-conjugating enzymes, it is thought that UEV3 may function as a negative regulator of polyubiquitination. UEV3 is expressed in various colon carcinoma cell lines, carcinomas of the uterine cervix and peripheral blood leukocytes as well as normal colon and cervical epithelium.
Images
| Immunofluorescence of paraffin embedded human breast cancer using UEVLD (GB112541) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded human cervical cancer using UEVLD (GB112541) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded human colon using UEVLD (GB112541) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded human endometrial cancer using UEVLD (GB112541) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded human gastric cancer using UEVLD (GB112541) at dilution of 1:650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
