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Anti-UNC5C Rabbit pAb (100 μl)
| Reactivity: | M,R & R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UNC5C rabbit polyclonal |
Gene Name: | Netrin receptor UNC5C |
Synonyms: | Protein unc-5 homolog 3, Protein unc-5 homolog C, Rostral cerebellar malformation protein, Unc5c, Rcm, Unc5h3 |
Immunogen: | Recombinant protein corresponding to Mouse UNC5C |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 103 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 800 | brain |
IHC | Rat | 1: 1000-1: 2000 | hippocampus |
Background
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
Images
| Western blot analysis of UNC5C (GB113588) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded rat hippocampus using UNC5C (GB113588) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
