Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | USP48 rabbit polyclonal |
Gene Name: | Ubiquitin carboxyl-terminal hydrolase 48 |
Synonyms: | Deubiquitinating enzyme 48, Ubiquitin thioesterase 48, Ubiquitin-specific-processing protease 48, Usp48, Kiaa4202, RAP1GA1, USP31 |
Immunogen: | Recombinant protein corresponding to Mouse USP48 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 121 kDa |
Observed MW. | 121 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | MCF-7, HeLa, HepG2, A549 |
Background
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites .
Images
Western blot analysis of USP48 (GB113011) at dilution of 1: 1000 Lane 1: HepG2 cell lysate Lane 2: MCF7 cell lysate | |
Western blot analysis of USP48 (GB113011) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: A549 cell lysate |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |