Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Ube2L6 rabbit polyclonal antibody |
Gene Name: | Ubiquitin/ISG15-conjugating enzyme E2 L6 |
Synonyms: | E2 ubiquitin-conjugating enzyme L6, UbcM8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, Ube2l6, Ubce8 |
Immunogen: | Recombinant protein corresponding to Mouse Ube2L6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 18 kDa |
Observed MW. | 18 kDa |
Uniprot ID: | Q9QZU9, Q4V8J2 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, spleen, lung |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
Images
Western blot analysis of UBE2L6 (GB112731) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |