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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | VAPB rabbit polyclonal |
Gene Name: | Vesicle-associated membrane protein-associated protein B |
Synonyms: | ALS8, VAMP associated protein B/C, VAMP-B, VAMP B/VAMP C, VAMP-C, VAP-B, VAP B/VAP C, VAP-C, VAPB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse VAPB |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 27 kDa |
Observed MW. | 27 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 1000 | heart, brain, liver |
Background
Vesicle-associated membrane protein-associated protein B (VAPB) is an integral membrane protein localized to the endoplasmic reticulum (ER) membrane. VAPB has been implicated in various cellular processes, including ER stress, the unfolded protein response (UPR) and calcium homeostasis regulation. The mutations in the gene of VAPB cause amyotrophic lateral sclerosis 8 (ALS8) and some other related forms of motor neuron disease including late onset spinal muscular atrophy.
Images
 | Western blot analysis of VAPB (GB113368) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
