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Anti-VEGF Receptor 2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | VEGF Receptor 2 rabbit polyclonal |
Gene Name: | Vascular endothelial growth factor receptor 2 |
Synonyms: | KDR, CD309, FLK1, VEGFR, VEGFR2, Kinase insert domain receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse VEGFR2 |
Isotype: | IgG |
Predicted MW. | 120 kDa |
Observed MW. | 120 kDa |
Purity: | Affinity purification |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | retina |
Background
This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Images
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Western blot analysis of VEGFR2 (GB11190) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
