Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Vinculin |
Synonyms: | Metavinculin, Vcl, CMD1W, CMH15, MVCL, MV, VINC |
Immunogen: | Recombinant protein corresponding to Human Vinculin |
Uniprot ID: | P18206 |
Isotype: | IgG1,k |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 117KDa / 124 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | uterine, heart, lung |
Background
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion.
Images
WB analysis of Vinculin(GB120003). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |