Reactivity: | H,M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Visfatin rabbit polyclonal |
Gene Name: | Nicotinamide phosphoribosyltransferase |
Synonyms: | 1110035O14Rik, NAmPRTase, NAMPT, PBEF, PBEF1, Pre-B-cell enhancing factor, VF, VISFATIN |
Immunogen: | Recombinant protein corresponding to Mouse Visfatin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 400-1: 800 | colon, kidney, heart, brain |
Background
Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Images
Immunohistochemistry analysis of paraffin-embedded human colon using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded mouse colon using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded rat colon using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded human kidney using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded mouse heart using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded rat heart using Visfatin (GB113478) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using Visfatin (GB113478) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |