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Anti-WDFY3 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | WDFY3 rabbit polyclonal antibody |
Gene Name: | WD repeat and FYVE domain-containing protein 3 |
Synonyms: | ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25, BWF1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse WDFY3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Membrane, Nucleus |
Uniprot ID: | Q8IZQ1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 400-1: 1300 | colon, colon cancer |
Background
WDFY3 also called ALFY, is a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy.This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
Images
 | Immunohistochemistry of paraffin embedded human colon using WDFY3 (GB111969) at dilution of 1:700 (400x lens) |
| Immunohistochemistry of paraffin embedded human colon cancer using WDFY3 (GB111969) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
