Reactivity: | M & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | WDR13 rabbit polyclonal antibody |
Gene Name: | WD repeat-containing protein 13 |
Synonyms: | Wdr13, located at OATL1, MG21 |
Immunogen: | Recombinant protein corresponding to Mouse WDR13 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 54 kDa |
Observed MW. | 54 kDa |
Uniprot ID: | Q91V09 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 1000-1: 2000 | lung, heart, kidney |
IHC/IF | Mouse, Rat | 1: 2500-1: 8000 | lung |
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese.
Images
Western blot analysis of WDR13 (GB112602) at dilution of 1: 1000 | |
Immunohistochemistry of paraffin embedded mouse lung using WDR13 (GB112602) at dilution of 1: 2500 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using WDR13 (GB112602) at dilution of 1: 2500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |