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Anti-WDR59 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | WDR59 rabbit polyclonal antibody |
Gene Name: | GATOR complex protein WDR59 |
Synonyms: | CUL4- and DDB1-associated WDR protein 12, WD repeat-containing protein 59, Wdr59, Cdw12 |
Immunogen: | Recombinant protein corresponding to Mouse WDR59 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 112 kDa |
Observed MW. | 112 kDa |
Uniprot ID: | Q8C0M0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, skeletal muscle |
Background
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
Images
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Western blot analysis of wdr59 (GB111121) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
