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Anti-WIPI1 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | WIPI1 rabbit polyclonal antibody |
Gene Name: | WD repeat domain phosphoinositide-interacting protein 1 |
Synonyms: | WIPI-1, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WD40 repeat protein interacting with phosphoinositides of 49 kDa, Wipi1, FLJ10055, ATG18, Atg18 protein homolog |
Immunogen: | Recombinant protein corresponding to Mouse WIPI1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 49 kDa |
Uniprot ID: | Q5MNZ9, Q8R3E3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | A375, NIH/3T3 |
Background
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.
Images
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Western blot analysis of WIPI1 (GB111616) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
