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Anti-Wilms Tumor Protein Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Wilms Tumor Protein rabbit polyclonal antibody |
Gene Name: | Wilms tumor protein homolog |
Synonyms: | AEWS-GUD, NPHS4, WAGR, WIT-2, WT33, Wilms tumor, WT1 |
Immunogen: | Recombinant protein corresponding to Mouse WT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P22561, P49952, P19544 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:100-1:300 | kidney, spleen, testis |
Background
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (By similarity). Regulates the expression of numerous target genes, including EPO . Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors.
Images
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Immunohistochemistry of paraffin embedded human kidney using WT1 (GB11382) at dilution of 1:200 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse kidney using WT1 (GB11382) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using WT1 (GB11382) at dilution of 1:200 (400x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using WT1 (GB11382) at dilution of 1:100 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spleen using WT1 (GB11382) at dilution of 1:100 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using WT1 (GB11382) at dilution of 1:100 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
