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Anti-alpha 1 Antitrypsin Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | alpha 1 Antitrypsin rabbit polyclonal antibody |
Gene Name: | Alpha-1-antitrypsin 1-2 |
Synonyms: | AAT, Alpha-1 protease inhibitor 2, Alpha-1-antiproteinase, Serine protease inhibitor 1-2, Serine protease inhibitor A1b, Serpin A1b, Serpina1b, Aat2, Dom2, Spi1-2 |
Immunogen: | Recombinant protein corresponding to Human alpha 1 Antitrypsin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | P22599 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1000 | liver, lung |
Background
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Images
 | Western blot analysis of SERPINA1 (GB112270) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
