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Anti-alpha Actinin 4 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | alpha Actinin 4 rabbit polyclonal |
Gene Name: | Alpha-actinin-4 |
Synonyms: | ACTININ 4, actinin, alpha 4, ACTN4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 105 kDa |
Observed MW. | 105kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 300-1: 1000 | liver, small intestine |
Background
ACTN4 (alpha actinin 4) is a ubiquitous actin-binding protein that cross-links actin filaments into bundles to form filopodia, and has a crucial role in cytoskeletal organization. ACTN4 is colocalized with actin stress fibers and is dispersed in the cytoplasm and in the nucleus. Increased levels of ACTN4 have been associated with cancer metastasis, indicating its implication in cancer cell migration and metastasis. Defects in ACTN4 cause glomerular disease. This antibody recognizes 100-105 kDa of endogenous ACTN4 protein in various lysates.
Images
| Western blot analysis of ACTN4 (GB113776) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
