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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Protein c-Fos |
Synonyms: | FOS, AP-1, C-p55, Fos proto-oncogene, AP-1 transcription factor subunit |
Immunogen: | Recombinant protein corresponding to Human c-Fos |
Uniprot ID: | P01100 |
Isotype: | IgG1,k |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 41 KDa / 62 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | HeLa |
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Images
| WB analysis of c-Fos（GB124125). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
