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| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | c-Jun rabbit polyclonal antibody |
Gene Name: | Transcription factor AP-1 |
Synonyms: | JUN, AP-1, AP1, c-Jun, Jun proto-oncogene, AP-1 transcription factor subunit, p39, Activator protein 1, Proto oncogene c Jun, JUNC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human c-Jun. |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P05412, P05627, P17325 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:1000-1:2000 | bone, kidney, lung, ovary, pancreas |
Background
c-Jun in combination with c-Fos, forms the AP-1 early response transcription factor. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function. It is known that c-jun plays a role in cellular proliferation and apoptosis of the endometrium throughout the menstrual cycle. The cyclic change of the c-jun protein levels is significant in the proliferation and apoptosis of glandular epithelial cells.
Images
 | Immunohistochemistry of paraffin embedded human kidney using c-Jun (GB11515) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse kidney using c-Jun (GB11515) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using c-Jun (GB11515) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry analysis of paraffin-embedded human kidney using c-Jun (GB11515) at dilution of 1:2000 |
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Immunohistochemistry of paraffin embedded rat kidney using JUN (GB11515) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using c-Jun (GB11515) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse ovary using c-Jun (GB11515) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse pancreas using JUN (GB11515) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat bone using JUN (GB11515) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
