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Anti-c-Kit Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | c-Kit rabbit polyclonal antibody |
Gene Name: | Mast/stem cell growth factor receptor Kit |
Synonyms: | KIT, C-Kit, CD117, PBT, SCFR, KIT proto-oncogene receptor tyrosine kinase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse c-Kit |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | P05532, P10721 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 200-1: 1000 | bone, colon, liver, liver cancer, testis, tonsil |
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
 | Immunohistochemistry of paraffin embedded human liver cancer using c-kit (GB11073-2) at dilution of 1:400 (400x lens) |
 | Immunohistochemistry of paraffin embedded human tonsil using c-kit (GB11073-2) at dilution of 1:400 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat colon using c-kit (GB11073-2) at dilution of 1:400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat liver using c-kit (GB11073-2) at dilution of 1:400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using c-kit (GB11073-2) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded rat bone using c-kit (GB11073-2) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
