Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | cIAP1 rabbit polyclonal antibody |
Gene Name: | Baculoviral IAP repeat-containing protein 2 |
Synonyms: | Cellular inhibitor of apoptosis 1, C-IAP1, Inhibitor of apoptosis protein 2, mIAP2, RING-type E3 ubiquitin transferase BIRC2, Birc2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse cIAP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 70 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q62210 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | spleen, testis |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 4000 | brain, colon, heart, kidney, liver cancer, lung, testis, uterus |
Background
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Images
Western blot analysis of Birc2 (GB112300) at dilution of 1: 1000 | |
Immunohistochemistry of paraffin embedded human colon using Birc2 (GB112300) at dilution of 1: 2100 (400x lens) | |
Immunohistochemistry of paraffin embedded human liver cancer using Birc2 (GB112300) at dilution of 1: 2100 (400x lens) | |
Immunohistochemistry of paraffin embedded rat heart using Birc2 (GB112300) at dilution of 1: 2100 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using Birc2 (GB112300) at dilution of 1: 2100 (400x lens) | |
Immunohistochemistry of paraffin embedded rat uterus using Birc2 (GB112300) at dilution of 1: 2100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using Birc2 (GB112300) at dilution of 1: 700 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using Birc2 (GB112300) at dilution of 1: 700 (400x lens) | |
Immunofluorescence of paraffin embedded rat kidney using Birc2 (GB112300) at dilution of 1: 700 (400x lens) | |
Immunofluorescence of paraffin embedded rat lung using Birc2 (GB112300) at dilution of 1: 700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |