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Anti-ch TOG Rabbit pAb (100 μl)
| Reactivity: | H,M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ch TOG rabbit polyclonal antibody |
Gene Name: | Cytoskeleton-associated protein 5 |
Synonyms: | ch TOG, CHTOG, CKAP5, cytoskeleton associated protein 5, MSPS, TOG, TOGp, XMAP215 |
Immunogen: | Recombinant protein corresponding to Mouse ch TOG |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Predicted MW. | 226 kDa |
Observed MW. | 250 kDa |
Uniprot ID: | A2AGT5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, | 1: 1000-1: 2000 | brain |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | brain, cerebellum, testis |
Background
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge.
Images
| Western blot analysis of CKAP5 (GB113955) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded mouse cerebellum using CKAP5 (GB113955) at dilution of 1: 700 (200x lens) |
 | Immunohistochemistry of paraffin embedded mouse testis using CKAP5 (GB113955) at dilution of 1: 1500 (200x lens) |
| Immunohistochemistry of paraffin embedded rat brain using CKAP5 (GB113955) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat cerebellum using CKAP5 (GB113955) at dilution of 1: 1500 (200x lens) |
| Immunohistochemistry of paraffin embedded rat testis using CKAP5 (GB113955) at dilution of 1: 1500 (200x lens) |
| Immunofluorescence of paraffin embedded embedded mouse brain using CKAP5 (GB113955) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse testis using CKAP5 (GB113955) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded embedded rat brain using CKAP5 (GB113955) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded embedded rat cerebellum using CKAP5 (GB113955) at dilution of 1: 1000 (200x lens) |
| Immunofluorescence of paraffin embedded embedded rat testis using CKAP5 (GB113955) at dilution of 1: 1000 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
