Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | hnRNPLL rabbit polyclonal antibody |
Gene Name: | Heterogeneous nuclear ribonucleoprotein L-like |
Synonyms: | Hnrnpll, BLOCK24, SRRF, Stromal RNA regulating factor |
Immunogen: | Recombinant protein corresponding to Mouse hnRNPLL |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q921F4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 2000 | heart, lung, spleen, testis |
Background
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC), a tyrosine phosphatase essential for T-cell development and activation.
Images
Immunohistochemistry of paraffin embedded mouse testis using HNRPLL (GB111848) at dilution of 1:1000 (350x lens) | |
Immunohistochemistry of paraffin embedded rat lung using HNRPLL (GB111848) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spleen using HNRPLL (GB111848) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat testis using HNRPLL (GB111848) at dilution of 1:1000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using HNRPLL (GB111848) at dilution of 1:700 (300x lens) | |
Immunofluorescence of paraffin embedded rat heart using HNRPLL (GB111848) at dilution of 1:700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |