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Anti-nmt55 / p54nrb Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R & H,M,R |
| Applications: | WB & IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | nmt55 / p54nrb rabbit polyclonal |
Gene Name: | Non-POU domain-containing octamer-binding protein |
Synonyms: | 55 kDa nuclear protein, NONO, NonO protein, NRB54, P54, p54(nrb), P54NRB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse nmt55 / p54nrb |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 55 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | liver, testis, brain |
IHC | Human, Mouse, Rat | 1: 2000-1: 4000 | lung cancer, colon cancer, brain, liver |
Background
Non-pou domain-containing octamer-binding protein(NONO), other named p54nrb, belongs to DBHS family, whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes, such as the regulation of circadian rhythm, carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ, and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components, pre-mRAN 3'-end formation, cAMP cycling and transcriptional activation.
Images
| Western blot analysis of p54nrb (GBGB113000) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human lung cancer using p54nrb (GBGB113000) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using p54nrb (GBGB113000) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using p54nrb (GBGB113000) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using p54nrb (GBGB113000) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse liver using p54nrb (GBGB113000) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
