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Anti-non-muscle Myosin IIB/MYH10 Mouse mAb (100 μl)
| Reactivity: | H,M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Myosin-10 |
Synonyms: | Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, MYH10, non-muscle IIb, NMMHC-B, NMMHC-IIB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MYH10 |
Uniprot ID: | Q61879 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Nuclear, Cytoplasm, Secreted |
Predicted MW. / Observed MW. | 229 kDa / 260 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | kidney, brain |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 4000 | brain, breast cancer, fetal rat |
Background
MYH10 (non-muscle II-b, NM IIB) is a member of non-muscle myosin II which plays fundamental roles in the maintenance of cell morphology, cell adhesion, and migration, as well as cell division. MYH10 is mainly present in nerve cells, megakaryocytes, and other non-muscle cells. It has been reported to mediate centrosome reorientation during cell migration and contribute to ciliogenesis. Overexpression of MYH10 has been observed in breast cancer.
Images
| Western blot analysis of MYH10 (GB121187) at dilution of 1: 1000 Lane 1: NIH3T3 cell lysate Lane 2: Mouse kidney tissue lysate Lane 3: Rat brain tissue lysate |
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| Immunohistochemistry analysis of paraffin-embedded human kidney using MYH10 (GB121187) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using MYH10 (GB121187) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using MYH10 (GB121187) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
