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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | p38 rabbit polyclonal |
Gene Name: | Mitogen-activated protein kinase 14 |
Synonyms: | Mitogen-activated protein kinase p38 alpha, MAP kinase 14, CRK1, Mapk14, MAP kinase p38 alpha, Crk1, Csbp1, Csbp2 |
Immunogen: | Recombinant protein corresponding to Mouse p38 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | placenta, heart, brain |
Background
P38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway, P38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using p38 (GB111058) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded mouse placenta using p38 (GB111058) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using p38 (GB111058) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
