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Anti-p38IP Rabbit pAb (100 μl)
| Reactivity: | M,R & M |
| Applications: | WB & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | p38IP rabbit polyclonal |
Gene Name: | Transcription factor SPT20 homolog |
Synonyms: | p38-interacting protein, p38IP, Supt20h, D3Ertd300e, Fam48a, Supt20 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse p38IP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 60 kDa |
Observed MW. | 60 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | testis, thymus, lung |
IF | Mouse | 1: 200-1: 400 | lung, brain substantia nigra, kidney |
Background
The FAM48A is required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.
Images
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Western blot analysis of p38IP (GB111466) at dilution of 1: 1000 Lane 1: Mouse testis tissue lysate Lane 2: Mouse thymus tissue lysate Lane 3: Mouse lung tissue lysate Lane 4: Rat testis tissue lysate Lane 5: Rat thymus tissue lysate Lane 6: Rat lung tissue lysate |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse lung usingp38IP (GB111466) at dilution of 1: 400 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain substantia nigra using p38IP (GB111466) at dilution of 1: 400 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using p38IP (GB111466) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
