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| Reactivity: | M,R & M,R & M,R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | p39 rabbit polyclonal |
| Gene Name: | Cyclin-dependent kinase 5 activator 2 |
| Synonyms: | Cdk5r2, CDK5R2, NCK5AI, P39, p39nck5ai, cyclin-dependent kinase 5, regulatory subunit 2 (p39), cyclin dependent kinase 5 regulatory subunit 2 |
| Immunogen: | Recombinant protein corresponding to Mouse p39 |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Subcellular location: | Cell membrane |
| Predicted MW. | 39 kDa |
| Observed MW. | 43 kDa |
| Uniprot ID: | O35926 |
Product Usage Information
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 | brain, hippocampus, cerebral cortex |
| IHC | Mouse, Rat | 1: 1500-1: 3000 | cerebellum |
| IF | Mouse, Rat | 1: 750-1: 1500 | cerebellum |
Background
Cyclin-dependent kinase 5 activator 2 is an enzyme encoded by the CDK5R2 gene. The protein is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
Images
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Western blot analysis of p39 (GB11792) at dilution of 1: 600 Lane 1: Mouse brain tissue lysate Lane 2: Mouse cerebral cortex tissue lysate Lane 3: Rat brain tissue lysate Lane 4: Rat cerebral cortex tissue lysate Lane 5: Rat hippocampus tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using p39 (GB11792) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using p39 (GB11792) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
