Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | p60 CAF1/MPP7 rabbit polyclonal antibody |
Gene Name: | Chromatin assembly factor 1 subunit B |
Synonyms: | CAF-1 subunit B, Chromatin assembly factor I p60 subunit, CAF-I 60 kDa subunit, CAF-I p60, CAF1A, CAF1P60, MPHOSPH7, MPP7, CHAF1B, M-phase phosphoprotein 7 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse p60 CAF1/MPP7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q13112, Q9D0N7 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | colon, spleen |
Background
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Images
Western blot analysis of CAF1B (GB112460) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |