Your shopping cart is empty!
Anti-Progesterone receptor Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Progesterone receptor rabbit polyclonal antibody |
Gene Name: | progesterone receptor |
Synonyms: | NR3C3, PGR, PR, progesterone receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to human Progesterone receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 99 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | P06401 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | breast, ovary, uterine |
Background
PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.
Images
 | Western blot analysis of Progesterone receptor (GB113972) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
