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Anti-Proteasome 19S S5A/ASF Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Proteasome 19S S5A/ASF rabbit polyclonal |
Gene Name: | 26S proteasome non-ATPase regulatory subunit 4 |
Synonyms: | AF, AF 1, Antisecretory factor 1, ASF, MCB1, PSMD4, pUB R5, Rpn10, S5A, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, Multiubiquitin chain-binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Proteasome 19S S5A/ASF |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41kDa |
Observed MW. | 55kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis |
Background
PSMD4, also named as MCB1, AF or ASF, belongs to the proteasome subunit S5A family. PSMD4 is a 50-kD subunit of the regulatory complex of the 26S proteasome. It binds and presumably selects ubiquitin-conjugates for destruction. PSMD4 displays selectivity for longer polyubiquitin chains. It modulates intestinal fluid secretion. PSMD4 is exposed on the sperm acrosomal surface, a notion that was further supported by the binding of non-cell permeant, biotinylated proteasomal inhibitor ZL3VS to the sperm acrosome. It is involved in the sperm-ZP penetration during fertilization. This antibody is specific to PSMD4.
Images
| Western blot analysis of PSMD4 (GB113795) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
