Your shopping cart is empty!
Anti-R51H2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | DNA repair protein RAD51 homolog 2 |
Synonyms: | hREC2, R51H2, RAD51 homolog B, RAD51 like 1 (S. cerevisiae), RAD51 like protein 1, RAD51B, RAD51L1, REC2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RAD51B |
Uniprot ID: | O35719 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 38 kDa / 38 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1500-1: 3000 | colon, brain, lung |
Background
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks.
Images
| Western blot analysis of RAD51B (GB115134) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
