Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RAB3GAP2 rabbit polyclonal antibody |
Gene Name: | Rab3 GTPase-activating protein non-catalytic subunit |
Synonyms: | Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunit, Kiaa0839, Rab3gap2, DKFZp434D245, FLJ14579 |
Immunogen: | Recombinantproteincorrespondingto Mouse RAB3GAP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 153 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | Q9H2M9, Q8BMG7 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | brain, lymph node |
Background
RAB3GAP2, also known as RAB3-GAP150, belongs to the Rab3-GAP regulatory subunit family. Rab3 GAP consists of two subunits: the catalytic subunit p130 and the noncatalytic subunit p150. Rab3 GAP is ubiquitously expressed and enriched in the synaptic soluble fraction of brain, consistent with it having a key role in neurodevelopment. RAB3-GAP150 forms the Rab3 GTPase-activating complex with RAB3-GAP130,where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. Defects in RAB3-GAP150 are the cause of Martsolf and Warburg Micro syndrome.
Images
Western blot analysis of RAB3GAP2 (GB111649) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |