Reactivity: | H & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Receptor activity-modifying protein 3 |
Synonyms: | CRLR activity modifying protein 3, Calcitonin receptor like receptor activity modifying protein 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RAMP3 |
Uniprot ID: | Q9WUP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 17 kDa / 47 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | MCF7 |
IHC/IF | Human | 1: 600-1: 1200 | ovarian cancer |
Background
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
Images
Western blot analysis of RAMP3 (GB114752) at dilution of 1: 300 | |
Immunohistochemistry analysis of paraffin embedded human ovarian cancer using RAMP3 (GB114752) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |