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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RGS2 rabbit polyclonal antibody |
Gene Name: | Regulator of G-protein signaling 2 |
Synonyms: | RGS2, Basic helix-loop-helix phosphoprotein G0S8, Cell growth inhibiting protein 31, G0/G1 switch regulatory protein 8 |
Immunogen: | Recombinant protein corresponding to Mouse RGS2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | O08849, Q9JHX0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, brain, spleen |
Background
The RGS2 Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
Images
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Western blot analysis of RGS2 (GB111404) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |