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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Regulator of G-protein signaling 6 |
Synonyms: | GAP, G protein signaling 6 regulator, GTPase activating protein, Regulator of G protein signaling 6, S914, FLJ43552 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RGS6 |
Uniprot ID: | Q9Z2H2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus, Cell membrane |
Product Usage Information
IHC/IF | Human | 1: 700-1: 2100 | liver cancer, colon |
Background
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity.
Images
| Immunohistochemistry analysis of paraffin embedded human liver cancer using RGS6 (GB115231) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin embedded human colon using RGS6 (GB115231) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
