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Anti-ROCK2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ROCK2 rabbit polyclonal antibody |
Gene Name: | Rho-associated protein kinase 2 |
Synonyms: | Rho kinase 2, coiled-coil-containing protein kinase 2, ROCK-II, KIAA0619, Rho-associated, p164 ROCK 2, Rock2m, ROKalpha, Rho kinase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to HumanROCK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 161 kDa |
Observed MW. | 180 kDa |
Uniprot ID: | O75116, P70336, Q62868 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, colon |
Background
ROCK2 is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. It is an isozyme of ROCK1, is a target for the small GTPase Rho. ROCK2 is localized in both cytoplasm and nucleus, and the nucleus-localized ROCK2 can target p300 for phosphorylation to regulate its acetyltransferase activity.
Images
| Western blot analysis of ROCK2 (GB111692) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
