Reactivity: | H,M,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RORA rabbit polyclonal antibody |
Gene Name: | Nuclear receptor ROR-alpha |
Synonyms: | Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, Rora, Nr1f1, Rzra |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RORA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 59 kDa |
Observed MW. | 67 kDa |
Uniprot ID: | P35398, P51448 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney, heart |
Background
The RORA is a steroid hormone receptor and has been implicated in the pathology of circadian rhythms, bone growth angiogenesis, development of cones, cellular metabolism and a mediator in the immune and lipid metabolism pathways. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1 .
Images
Western blot analysis of RORA (GB111300) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |