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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Raf1 rabbit polyclonal antibody |
Gene Name: | RAF proto-oncogene serine/threonine-protein kinase |
Synonyms: | Raf1, RAF1, Raf-1 proto-oncogene, serine/threonine kinase, CMD1NN, CRAF, NS5, c-Raf |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Raf1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 73 kDa |
Uniprot ID: | P04049, Q99N57, P11345 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1500 | muscle, testis, ovary |
Background
RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme[4] that in humans is encoded by the RAF1 gene. The c-Raf protein is part of the ERK1/2 pathway as a MAP kinase kinase kinase (MAP3K) that functions downstream of the Ras subfamily of membrane associated GTPases. C-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases, from the TKL (Tyrosine-kinase-like) group of kinases.
Images
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Western blot analysis of RAF-1 (GB11780) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
