Reactivity: | H,M,R & H,M |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RanBP17 rabbit polyclonal antibody |
Gene Name: | Ran-binding protein 17 |
Synonyms: | Ranbp17, Exp7, Exportin7, XPO7 |
Immunogen: | Recombinant protein corresponding to Mouse RanBP17 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 124 kDa |
Observed MW. | 124 kDa |
Uniprot ID: | Q99NF8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 250-1: 500 | testis |
Background
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.
Images
Western blot analysis of RANBP17 (GB112391) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |