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Anti-RanBP9 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RanBP9 rabbit polyclonal |
Gene Name: | Ran-binding protein 9 |
Synonyms: | BPM L, BPM90, Ran binding protein M, RanBP7, RANBP9, RANBPM, IBAP-1, B-cell antigen receptor Ig beta-associated protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse RanBP9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 2000-1: 4000 | heart, testis |
Background
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse heart using RanBP9 (GB113228) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse testis using RanBP9 (GB113228) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
