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Anti-RhoA + RhoC Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RhoA + RhoC rabbit polyclonal antibody |
Gene Name: | Transforming protein RhoA Gene |
Synonyms: | ARH12, ARHA, h12, Rho cDNA clone 12, RHO12, RHOA, RHOH12, Transforming protein RhoA |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RhoA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 23 kDa |
Observed MW. | 23 kDa |
Uniprot ID: | Q9QUI0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney, lung |
Background
RhoA is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of RhoA is associated with tumor cell proliferation and metastasis. RhoA signalling is critical to many cellular processes including migration, mechanotransduction, and is often disrupted in carcinogenesis.
Images
 | Western blot analysis of RhoA (GB114058) at dilution of 1: 1000 |
 | Western blot analysis of RhoA (GB114058) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
