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Anti-Ribonuclease 3/ECP Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ribonuclease 3/ECP rabbit polyclonal antibody |
Gene Name: | Eosinophil cationic protein |
Synonyms: | ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3, Cytotoxic ribonuclease |
Immunogen: | Recombinant protein corresponding to Human Ribonuclease 3/ECP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 18 kDa |
Observed MW. | 18 kDa |
Uniprot ID: | P70709 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | bone marrow |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | bone, brain, spleen |
Background
Eosinophil Cationic Protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil cationic protein is encoded by the RNASE3 gene. ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body.
Images
| Western blot analysis of ECP (GB112150) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded mouse bone using ECP (GB112150) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse spleen using ECP (GB112150) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat bone using ECP (GB112150) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spleen using ECP (GB112150) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded rat bone using ECP (GB112150) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded rat brain using ECP (GB112150) at dilution of 1: 1000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
