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Anti-SDCCAG8 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Serologically defined colon cancer antigen 8 homolog |
Synonyms: | Antigen NY CO 8, BBS16, CCCAP, hCCCAP, HSPC085, NY CO 8, SDCCAG8 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SDCCAG8 |
Uniprot ID: | Q80UF4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 3000 | colon cancer, ovary, thymus gland |
Background
Plays a role in the establishment of cell polarity and epithelial lumen formation. Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Images
| Immunohistochemistry analysis of paraffin embedded human colon cancer using SDCCAG8 (GB114950) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat ovary using SDCCAG8 (GB114950) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse ovary using SDCCAG8 (GB114950) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse thymus gland using SDCCAG8 (GB114950) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
