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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SDPR rabbit polyclonal antibody |
Gene Name: | Caveolae-associated protein 2 |
Synonyms: | Cavin-2, Phosphatidylserine-binding protein, Serum deprivation-response protein, Sdpr, PS p68, SDR |
Immunogen: | Recombinant protein corresponding to Mouse SDPR |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q63918, Q66H98 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 2000 | brain, heart, kidney, liver |
Background
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
Images
| Immunohistochemistry of paraffin embedded mouse heart using SDPR (GB111994) at dilution of 1:650 (250x lens) |
| Immunohistochemistry of paraffin embedded mouse liver using SDPR (GB111994) at dilution of 1:650 (300x lens) |
| Immunohistochemistry of paraffin embedded rat brain using SDPR (GB111994) at dilution of 1:800 (200x lens) |
| Immunohistochemistry of paraffin embedded rat liver using SDPR (GB111994) at dilution of 1:650 (200x lens) |
| Immunohistochemistry of paraffin embedded rat heart using SDPR (GB111994) at dilution of 1:650 (250x lens) |
| Immunofluorescence of paraffin embedded human kidney using SDPR (GB111994) at dilution of 1:650 (250x lens) |
| Immunofluorescence of paraffin embedded mouse liver using SDPR (GB111994) at dilution of 1:650 (300x lens) |
| Immunofluorescence of paraffin embedded rat liver using SDPR (GB111994) at dilution of 1:650 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
